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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
14.5 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Hspg2  perlecan (heparan sulfate proteoglycan 2)   (Synonyms: Pcn, per, perlecan, Plc)
Results  Reference
1J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51
1*J:55507 French MM, Smith SE, Akanbi K, Sanford T, Hecht J, Farach-Carson MC, Carson DD, Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro. J Cell Biol. 1999 May 31;145(5):1103-15
1*J:227060 Fujikawa K, Yokohama-Tamaki T, Morita T, Baba O, Qin C, Shibata S, An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage. Eur J Histochem. 2015;59(3):2553
1J:195888 Gustafsson E, Almonte-Becerril M, Bloch W, Costell M, Perlecan maintains microvessel integrity in vivo and modulates their formation in vitro. PLoS One. 2013;8(1):e53715
1J:311849 Hirata A, Katayama K, Tsuji T, Natsume N, Sugahara T, Koga Y, Takano K, Otsuki Y, Nakamura H, Heparanase localization during palatogenesis in mice. Biomed Res Int. 2013;2013:760236
1J:227320 Holtz AM, Griffiths SC, Davis SJ, Bishop B, Siebold C, Allen BL, Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function. J Cell Biol. 2015 Jun 8;209(5):739-57
1J:345111 Jacobson KR, Saleh AM, Lipp SN, Tian C, Watson AR, Luetkemeyer CM, Ocken AR, Spencer SL, Kinzer-Ursem TL, Calve S, Extracellular matrix protein composition dynamically changes during murine forelimb development. iScience. 2024 Feb 16;27(2):108838
1*J:111788 Kiyozumi D, Sugimoto N, Sekiguchi K, Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11981-6
1J:335095 Lipp SN, Jacobson KR, Schwaderer AL, Hains DS, Calve S, FOXD1 is required for 3D patterning of the kidney interstitial matrix. Dev Dyn. 2023 Apr;252(4):463-482
1J:161883 Sasse P, Malan D, Fleischmann M, Roell W, Gustafsson E, Bostani T, Fan Y, Kolbe T, Breitbach M, Addicks K, Welz A, Brem G, Hescheler J, Aszodi A, Costell M, Bloch W, Fleischmann BK, Perlecan is critical for heart stability. Cardiovasc Res. 2008 Dec 1;80(3):435-44
1J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory